Sure.
But I believe much of the trade will be with your hometown, and as such could require very little micromanagement.. if any.
It could be as easy as setting a few ships aside for the trade. But Landtrade will also feature.. we know that fronm the pics, or atleast something that looked very much like tradecarts.
Note: You could break those, and the contents spilled! Ie destroy other nations tradecarts, and you can plunder!!
Or atleast thats what it looked like to me